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Health and Social Person-centric Ontology
Last uploaded:
June 9, 2023
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| Preferred Name | Crush Syndrome | |
| Synonyms |
Bywater's syndrome traumatic rhabdomyolysis |
|
| Definitions |
Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_1001299 |
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| database_cross_reference |
SNOMEDCT:23697004 MeSH:D003444 MedDRA:10050702
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|
| definition |
Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
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| has_exact_synonym |
Bywater's syndrome traumatic rhabdomyolysis
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|
| label |
Crush Syndrome
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|
| preferred label |
Crush Syndrome
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|
| prefixIRI |
efo1:EFO_1001299
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|
| prefLabel |
Crush Syndrome
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|
| term editor |
Dani Welter
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| subClassOf |
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