loading...| Preferred Name | Stasis dermatitis | |
| Synonyms |
Varicose eczema Venous eczema |
|
| Definitions |
Stasis dermatitis commonly occurs in older age. It is caused by venous hypertension resulting from retrograde flow due to incompetent venous valves, valve destruction, or obstruction of the venous system. Further tissue changes arise from an inflammatory process mediated by metalloproteinases, which are up-regulated by ferric ion from extravasated red blood cells. Stasis dermatitis presents initially as poorly demarcated erythematous plaques of the lower legs bilaterally, classically involving the medial malleolus. |
|
| ID |
http://purl.obolibrary.org/obo/HP_0033564 |
|
| dc_date |
2021-01-23T12:54:26Z |
|
| definition |
Stasis dermatitis commonly occurs in older age. It is caused by venous hypertension resulting from retrograde flow due to incompetent venous valves, valve destruction, or obstruction of the venous system. Further tissue changes arise from an inflammatory process mediated by metalloproteinases, which are up-regulated by ferric ion from extravasated red blood cells. Stasis dermatitis presents initially as poorly demarcated erythematous plaques of the lower legs bilaterally, classically involving the medial malleolus. |
|
| has_exact_synonym |
Varicose eczema Venous eczema |
|
| has_obo_namespace |
human_phenotype |
|
| id |
HP:0033564 |
|
| label |
Stasis dermatitis |
|
| notation |
HP:0033564 |
|
| prefLabel |
Stasis dermatitis |
|
| terms_creator | ||
| treeView | ||
| subClassOf |