Human Phenotype Ontology

Last uploaded: August 13, 2024
Preferred Name

Hypersensitivity pneumonitis
Synonyms
Definitions

Hypersensitivity pneumonitis involves inhalation of an antigen. This leads to an exaggerated immune response and a following inflammation of the alveoli within the lungs. The main feature of chronic hypersensitivity pneumonitis on lung biopsies is expansion of the interstitium by lymphocytes accompanied by an occasional multinucleated giant cell or loose granuloma. After exposure to the provoking antigen, following symptoms can be seen: fever, chills, malaise, cough, hemoptysis, chest tightness, dyspnea, rash, swelling and headache and can be completely reversible, based on the duration of the illness, categorized as acute (HP:0011009), subacute (HP:0011011), and chronic (HP:0011010). Hypersensitivity pneumonitis may also be called many different names, based on the provoking antigen.

ID

http://purl.obolibrary.org/obo/HP_0006516

comment

Hypersensitivity pneumonitis may also be called many different names, based on the provoking antigen.

database_cross_reference

UMLS:C0002390

SNOMEDCT_US:37471005

definition

Hypersensitivity pneumonitis involves inhalation of an antigen. This leads to an exaggerated immune response and a following inflammation of the alveoli within the lungs. The main feature of chronic hypersensitivity pneumonitis on lung biopsies is expansion of the interstitium by lymphocytes accompanied by an occasional multinucleated giant cell or loose granuloma. After exposure to the provoking antigen, following symptoms can be seen: fever, chills, malaise, cough, hemoptysis, chest tightness, dyspnea, rash, swelling and headache and can be completely reversible, based on the duration of the illness, categorized as acute (HP:0011009), subacute (HP:0011011), and chronic (HP:0011010).

has_obo_namespace

human_phenotype

id

HP:0006516

label

Hypersensitivity pneumonitis

notation

HP:0006516

prefLabel

Hypersensitivity pneumonitis

treeView

http://purl.obolibrary.org/obo/HP_0006530

subClassOf

http://purl.obolibrary.org/obo/HP_0006530

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