Preferred Name |
Aganglionic megacolon |
|
Synonyms |
Hirschsprung megacolon Enlarged colon lacking nerve cells Megacolon Congenital megacolon Hirschsprung disease |
|
Definitions |
Aganglionic megacolon is characterized by congenital absence of intrinsic ganglion cells in the myenteric (Auerbach) and submucosal (Meissner) plexuses of the gastrointestinal tract. An abnormality resulting from a lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) that results in bowel obstruction with enlargement of the colon. |
|
ID |
http://purl.obolibrary.org/obo/HP_0002251 |
|
comment |
Aganglionic megacolon is characterized by congenital absence of intrinsic ganglion cells in the myenteric (Auerbach) and submucosal (Meissner) plexuses of the gastrointestinal tract. |
|
database_cross_reference |
UMLS:C0019569 MSH:D008531 SNOMEDCT_US:33995003 SNOMEDCT_US:204739008 SNOMEDCT_US:367495003 MEDDRA:10027110 MSH:D006627 UMLS:C0025160 |
|
definition |
An abnormality resulting from a lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) that results in bowel obstruction with enlargement of the colon. |
|
has_alternative_id |
HP:0002029 HP:0002030 HP:0002606 HP:0004391 |
|
has_exact_synonym |
Hirschsprung megacolon Enlarged colon lacking nerve cells Megacolon Congenital megacolon |
|
has_obo_namespace |
human_phenotype |
|
has_related_synonym |
Hirschsprung disease |
|
id |
HP:0002251 |
|
in_subset | ||
label |
Aganglionic megacolon |
|
notation |
HP:0002251 |
|
prefLabel |
Aganglionic megacolon |
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treeView | ||
subClassOf |