Homeostasis imbalance process ontology

Last uploaded: April 3, 2024
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Preferred Name

leflunomide
Synonyms

leflunomidum

5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide

5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide

leflunomide

leflunomida

Arava

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide

Leflunomide

5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
Definitions

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
ID

http://purl.obolibrary.org/obo/CHEBI_6402
database cross reference

PMID:15385935

CAS:75706-12-6

PMID:16778342

PMID:11391470

PMID:19715969

DrugBank:DB01097

PMID:16202258

PMID:19190124

PMID:18663553

PMID:9777697

Drug_Central:1552

PMID:18173611

PMID:15537652

PMID:11067959

PMID:17366662

PMID:11718154

PMID:15789891

PMID:15489872

PMID:15188371

PMID:15652966

PMID:11475244

PMID:11053058

PMID:19344337

Reaxys:4323174

PMID:11333342

Beilstein:4323174

PMID:10890256

PMID:16645972

LINCS:LSM-3771

PMID:11043056

PMID:15127974

PMID:17604599

PMID:11994686

PMID:9075844

PMID:16769661

PMID:14622739

PMID:16284916

PMID:10515382

PMID:15127968

PMID:18034546

PMID:15030575

PMID:11522581

PMID:17646975

PMID:11876141

PMID:12017890

PMID:16638062

PMID:15934905

PMID:18688040

PMID:15899055

PMID:12074690

PMID:8610393

PMID:10702725

PMID:18413415

PMID:11707749

PMID:7496341

PMID:19751817

PMID:15214907

PMID:16106593

PMID:19581389

PMID:15665760

PMID:12833393

PMID:19770782

PMID:19169882

PMID:9123314

PMID:16638420

PMID:16142756

PMID:9625011

PMID:17854740

PMID:11884931

PMID:16688677

PMID:11271257

PMID:11340750

PMID:7676489

PMID:18496682
definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
has role

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_37153

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_38637

http://purl.obolibrary.org/obo/CHEBI_68542

http://purl.obolibrary.org/obo/CHEBI_68543

http://purl.obolibrary.org/obo/CHEBI_50908

http://purl.obolibrary.org/obo/CHEBI_35475

http://purl.obolibrary.org/obo/CHEBI_35442

http://purl.obolibrary.org/obo/CHEBI_50266
has_exact_synonym

Leflunomide

5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
has_related_synonym

leflunomidum

5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide

5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide

leflunomide

leflunomida

Arava

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide
label

leflunomide
prefixIRI

CHEBI:6402
prefLabel

leflunomide
subClassOf

http://purl.bioontology.org/ontology/HOIP/HOIP_0031087
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_6402 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 COVID-19 SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6402 ODNAE SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1128 NCIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042253 PDQ LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00471 COID LOOM
http://www.co-ode.org/ontologies/galen#Leflunomide GALEN LOOM
http://purl.bioontology.org/ontology/VANDF/4021132 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148586 NDFRT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148586 ODAE LOOM
http://purl.bioontology.org/ontology/LNC/LP34970-1 LOINC LOOM
http://purl.bioontology.org/ontology/NDDF/007642 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386981009 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14180 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D000077339 MESH LOOM
http://stirdf.jst.go.jp/id/200907020767739835 IOBC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026142 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C045463 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB01097 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0063041 OCHV LOOM
https://go.drugbank.com/drugs/DB01097 MDM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU017708 LOINC LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02536 MIO LOOM
http://purl.jp/bio/4/id/200906002440684105 IOBC LOOM
http://bmi.utah.edu/ontologies/peontology/C0063041 RAO LOOM
http://purl.obolibrary.org/obo/NCIT_C1128 BERO LOOM
http://purl.bioontology.org/ontology/RXNORM/27169 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/L04AK01 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_6402 ODNAE LOOM