loading...| Preferred Name | azathioprine | |
| Synonyms |
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine Imuran (TN) 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine |
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| Definitions |
A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2948 |
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| database cross reference |
PMID:9345422 PMID:16397313 PMID:9273463 PMID:19243907 PMID:25248004 PMID:28166217 PMID:15199672 PMID:8738760 PMID:17970886 PMID:18336531 PMID:20080917 PMID:11064448 Reaxys:1225351 PMID:25641386 CAS:446-86-6 PMID:15476481 PMID:25314066 PMID:18008354 PMID:25440430 PMID:15973722 PMID:17381669 PMID:16764353 PMID:25443086 PMID:25581826 PMID:16344342 PMID:16954801 Drug_Central:269 PMID:15628319 DrugBank:DB00993 |
|
| definition |
A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. |
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| has role |
http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_50903 |
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| has_exact_synonym |
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine |
|
| has_related_synonym |
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine Imuran (TN) 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine |
|
| label |
azathioprine |
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| prefixIRI |
CHEBI:2948 |
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| prefLabel |
azathioprine |
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| subClassOf |