Reviewed: Trowsdale, J, Bluestone, JA, Elliott, T, Esensten, J, Heemskerk, JW, 2011-05-28 Adaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with remarkable diversity tailored to recognize aspects of particular pathogens or antigens. During infection, dendritic cells (DC) which act as sentinels in the peripheral tissues recognize and pick up the pathogen in the form of antigenic determinants and then process these antigens and present them to T cells. These T cells of appropriate specificity respond to the antigen, and either kill the pathogen directly or secrete cytokines that will stimulate B lymphocyte response. B cells provide humoral immunity by secreting antibodies specific for the pathogen or antigen. Authored: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22 Edited: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22

http://purl.obolibrary.org/obo/HINO_0026239

Reviewed: Trowsdale, J, Bluestone, JA, Elliott, T, Esensten, J, Heemskerk, JW, 2011-05-28

Adaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with remarkable diversity tailored to recognize aspects of particular pathogens or antigens. During infection, dendritic cells (DC) which act as sentinels in the peripheral tissues recognize and pick up the pathogen in the form of antigenic determinants and then process these antigens and present them to T cells. These T cells of appropriate specificity respond to the antigen, and either kill the pathogen directly or secrete cytokines that will stimulate B lymphocyte response. B cells provide humoral immunity by secreting antibodies specific for the pathogen or antigen.

Authored: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22

Edited: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22

Pubmed16551257

Reactome, http://www.reactome.org

Pubmed11861602

Pubmed21682741

Adaptive Immune System

http://purl.obolibrary.org/obo/NCBITaxon_9606

HINO:0026239

Adaptive Immune System

ReactomeREACT_75774

Reactome Database ID Release 431280218

http://purl.obolibrary.org/obo/INO_0000021

http://purl.obolibrary.org/obo/HINO_0022374

http://purl.obolibrary.org/obo/HINO_0022379

http://purl.obolibrary.org/obo/HINO_0022392

http://purl.obolibrary.org/obo/HINO_0022397

http://purl.obolibrary.org/obo/HINO_0022399

http://purl.obolibrary.org/obo/HINO_0026233

http://purl.obolibrary.org/obo/HINO_0026227