Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

MRN complex relocalizes to nuclear foci
Synonyms
Definitions

Authored: Matthews, L, 2003-11-23 12:20:00 MRN complexes localize to nuclear foci in response to double-strand breaks and have been implicated in DNA end-processing during homologous recombination repair (Trujillo et al., 1998). The MRN complex may function as a bridge between double-strand break ends through interactions between the coiled-coil domains of RAD50 (Hoptner et al., 2002).

ID

http://purl.obolibrary.org/obo/HINO_0016469

comment

Authored: Matthews, L, 2003-11-23 12:20:00

MRN complexes localize to nuclear foci in response to double-strand breaks and have been implicated in DNA end-processing during homologous recombination repair (Trujillo et al., 1998). The MRN complex may function as a bridge between double-strand break ends through interactions between the coiled-coil domains of RAD50 (Hoptner et al., 2002).

definition source

Reactome, http://www.reactome.org

Pubmed12152085

Pubmed9705271

Pubmed9554850

label

MRN complex relocalizes to nuclear foci

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016469

prefLabel

MRN complex relocalizes to nuclear foci

seeAlso

ReactomeREACT_1884

Reactome Database ID Release 4383572

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0025079

http://purl.obolibrary.org/obo/HINO_0016466

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http://scai.fraunhofer.de/PWDICT#ID1632 PTS LOOM