Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Homologous Recombination Repair
Synonyms
Definitions

The HRR pathway is an "error free" DNA repair mechanism that utilizes information encoded by homologous sequence to repair double-strand breaks (DSBs). HRR acts on DSBs occurring within replicated DNA (replication-independent DSBs) or on DSBs that are generated at broken replication forks (replication-dependent DSBs). Repair by homologous recombination involves processing of the ends of the DNA double-strand break, homologous DNA pairing and strand exchange, repair DNA synthesis, and resolution of the heteroduplex molecules. Edited: Matthews, L, 0000-00-00 00:00:00 Authored: Thompson, L, 2003-07-14 15:03:24 Reviewed: West, SC, 0000-00-00 00:00:00

ID

http://purl.obolibrary.org/obo/HINO_0016455

comment

The HRR pathway is an "error free" DNA repair mechanism that utilizes information encoded by homologous sequence to repair double-strand breaks (DSBs). HRR acts on DSBs occurring within replicated DNA (replication-independent DSBs) or on DSBs that are generated at broken replication forks (replication-dependent DSBs). Repair by homologous recombination involves processing of the ends of the DNA double-strand break, homologous DNA pairing and strand exchange, repair DNA synthesis, and resolution of the heteroduplex molecules.

Edited: Matthews, L, 0000-00-00 00:00:00

Authored: Thompson, L, 2003-07-14 15:03:24

Reviewed: West, SC, 0000-00-00 00:00:00

definition source

Pubmed11376695

Reactome, http://www.reactome.org

Pubmed11242102

Pubmed12427531

Pubmed12954758

label

Homologous Recombination Repair

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016455

prefLabel

Homologous Recombination Repair

seeAlso

GENE ONTOLOGYGO:0000724

Reactome Database ID Release 4373888

ReactomeREACT_1874

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0016701

http://purl.obolibrary.org/obo/HINO_0016460

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