loading...| Preferred Name |
BoNT Light Chain Types A, C1, E cleave SNAP-25 |
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| Synonyms |
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| Definitions |
BoNTs of serotypes A, C1 and E cleave SNAP-25 (synaptosomal-associated protein, 25kDa), a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. BoNT A removes nine amino-acid residues from the carboxyl terminus, whereas BoNT E removes 26 C-terminal amino-acid residues (Bajohrs et al.,2004). Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0015706 |
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| comment |
BoNTs of serotypes A, C1 and E cleave SNAP-25 (synaptosomal-associated protein, 25kDa), a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. BoNT A removes nine amino-acid residues from the carboxyl terminus, whereas BoNT E removes 26 C-terminal amino-acid residues (Bajohrs et al.,2004). Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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| definition source |
Pubmed8294407 Pubmed9886085 Reactome, http://www.reactome.org Pubmed8611567 Pubmed8243676 Pubmed15486565 |
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| label |
BoNT Light Chain Types A, C1, E cleave SNAP-25 |
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| prefixIRI |
HINO:0015706 |
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| prefLabel |
BoNT Light Chain Types A, C1, E cleave SNAP-25 |
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| seeAlso |
ReactomeREACT_11240 Reactome Database ID Release 43181546 |
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| has_part |
http://purl.obolibrary.org/obo/HINO_0026747 |