Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
Synonyms
Definitions

Authored: Matthews, L, 2006-05-15 07:16:46 Reviewed: Zhao, RY, 2006-07-11 22:08:52 In one model of Vpr mediated induction of apoptosis, Vpr acts directly on the mitochondrial permeability transition pore complex through its interaction with adenine nucleotide translocator (ANT). This interaction promotes the permeabiliztion of the mitochondrial membranes resulting in the release of cytochrome c and apoptosis-inducing factors. Edited: Matthews, L, 2006-06-02 10:55:44

ID

http://purl.obolibrary.org/obo/HINO_0015682

comment

Authored: Matthews, L, 2006-05-15 07:16:46

Reviewed: Zhao, RY, 2006-07-11 22:08:52

In one model of Vpr mediated induction of apoptosis, Vpr acts directly on the mitochondrial permeability transition pore complex through its interaction with adenine nucleotide translocator (ANT). This interaction promotes the permeabiliztion of the mitochondrial membranes resulting in the release of cytochrome c and apoptosis-inducing factors.

Edited: Matthews, L, 2006-06-02 10:55:44

definition source

Reactome, http://www.reactome.org

Pubmed10620603

label

Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0015682

prefLabel

Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization

seeAlso

ReactomeREACT_8016

Reactome Database ID Release 43180897

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0027449

http://purl.obolibrary.org/obo/HINO_0027447

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http://scai.fraunhofer.de/PWDICT#ID2040 PTS LOOM