loading...| Preferred Name |
eosinophil |
|
| Synonyms |
polymorphonuclear leucocyte polymorphonuclear leukocyte eosinophilic leucocyte eosinophilic granulocyte eosinophilic leukocyte eosinocyte |
|
| Definitions |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
|
| ID |
http://purl.obolibrary.org/obo/CL_0000771 |
|
| comment |
Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
|
| alternative label |
polymorphonuclear leucocyte polymorphonuclear leukocyte eosinophilic leucocyte eosinophilic granulocyte eosinophilic leukocyte eosinocyte |
|
| database_cross_reference |
CALOHA:TS-0279 MESH:D004804 BTO:0000399 FMA:62861 |
|
| definition |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
|
| has broad synonym |
polymorphonuclear leucocyte polymorphonuclear leukocyte |
|
| has exact synonym |
eosinophilic leucocyte eosinophilic granulocyte eosinophilic leukocyte eosinocyte |
|
| has part |
http://purl.obolibrary.org/obo/PR_000001343 http://purl.obolibrary.org/obo/PR_000001307 http://purl.obolibrary.org/obo/PR_000005178 |
|
| has plasma membrane part |
http://purl.obolibrary.org/obo/PR_000001343 http://purl.obolibrary.org/obo/PR_000001307 http://purl.obolibrary.org/obo/PR_000005178 |
|
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim |
|
| label |
eosinophil |
|
| note |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
|
| overlaps |
http://purl.obolibrary.org/obo/PR_000001343 http://purl.obolibrary.org/obo/PR_000001307 http://purl.obolibrary.org/obo/PR_000005178 |
|
| preferred label |
eosinophil |
|
| prefixIRI |
CL:0000771 |
|
| prefLabel |
eosinophil |
|
| present_in_taxon | ||
| textual definition |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. |
|
| subClassOf |