loading...| Preferred Name |
goserelin |
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| Synonyms |
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| Definitions |
A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_5523 |
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| ATC Code |
L02AE03 |
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| ChEBI ID | ||
| definition |
A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. A synthetic long-acting agonist of gonadotropin-releasing hormone. Goserelin is used in treatments of malignant neoplasms of the prostate, uterine fibromas, and metastatic breast cancer. |
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| has database cross reference | ||
| label |
goserelin |
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| MeSH Descriptor ID | ||
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| prefixIRI |
CHEBI:5523 |
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| prefLabel |
goserelin |
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| SNOMED CT Identifier | ||
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