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Gender, Sex, and Sexual Orientation Ontology
| Preferred Name | cyproterone acetate | |
| Synonyms |
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| Definitions |
An agent with anti-androgen and progestational properties. It shows competitive binding with dihydrotestosterone at androgen receptor sites. The acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_50743 |
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| ATC Code |
G03HA01
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| ChEBI ID | ||
| definition |
An agent with anti-androgen and progestational properties. It shows competitive binding with dihydrotestosterone at androgen receptor sites. The acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels.
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| has database cross reference | ||
| is referenced by | ||
| label |
cyproterone acetate
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| MeSH Descriptor ID | ||
| name |
CPA
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| NCI Thesaurus ID | ||
| prefixIRI |
CHEBI:50743
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| prefLabel |
cyproterone acetate
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| RxNorm ID | ||
| short name |
CPA
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| SNOMED CT Identifier | ||
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_47622 http://purl.obolibrary.org/obo/CHEBI_77175 http://purl.obolibrary.org/obo/CHEBI_36885 |
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