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Gene Ontology Extension
| Preferred Name | post-translational protein modification | |
| Synonyms |
PTM post-translational amino acid modification posttranslational amino acid modification posttranslational protein modification posttranslational modification post-translational modification |
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| Definitions |
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term. |
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| ID |
http://purl.obolibrary.org/obo/GO_0043687 |
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| comment |
This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
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| database_cross_reference |
Reactome:1393143 Reactome:1521120 Reactome:1417626 Reactome:1471181 Reactome:1417625 Reactome:1373126 Reactome:1326819 Wikipedia:Posttranslational_modification Reactome:1326820 Reactome:1526886 Reactome:1514375 Reactome:1450726 Reactome:1532702 Reactome:1393142 Reactome:1253304 Reactome:1299104 Reactome:1450725 Reactome:1352921 Reactome:1536108 Reactome:163841 Reactome:1496988 Reactome:1483173 Reactome:1521250 Reactome:597592 Reactome:1373127 Reactome:1471338 Reactome:1352920 Reactome:1496876 Reactome:1280244 Reactome:1536063 Reactome:1526966 Reactome:1532615 Reactome:1299103 Reactome:1514269 Reactome:1253303 Reactome:1280243
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| definition |
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
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| has_exact_synonym |
PTM post-translational amino acid modification posttranslational amino acid modification posttranslational protein modification posttranslational modification post-translational modification
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| has_obo_namespace |
biological_process
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| id |
GO:0043687
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| in_subset | ||
| label |
post-translational protein modification
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| notation |
GO:0043687
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| prefLabel |
post-translational protein modification
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