loading...| Preferred Name | desmosome | |
| Synonyms |
macula adherens spot desmosome |
|
| Definitions |
A cell-cell junction in which - on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins - a bundle of keratin intermediate filaments is attached to the surface of each plaque - transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0030057 |
|
| altLabel |
macula adherens spot desmosome |
|
| definition |
A cell-cell junction in which - on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins - a bundle of keratin intermediate filaments is attached to the surface of each plaque - transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
|
| hasOBONamespace |
cellular_component |
|
| id |
GO:0030057 |
|
| notation |
GO:0030057 |
|
| prefLabel |
desmosome |
|
| relatedMatch |
Wikipedia:Desmosome |
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| subClassOf |