loading...| Preferred Name | carcinoid tumor | |
| Synonyms |
neuroendocrine tumour G1 carcinoid tumour (disease) neuroendocrine neoplasm G1 carcinoid tumor (disease) carcinoid tumor neuroendocrine tumor G1 NET G1 carcinoid |
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| Definitions |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0005369 |
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| comment |
Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources |
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| exactMatch |
http://identifiers.org/snomedct/443492008 |
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| hasDbXref |
ICDO:8241/3 MESH:D002276 ICD9:209.60 SCTID:443492008 EFO:0004243 ICDO:8240/3 HP:0100570 NCIT:C2915 |
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| hasExactSynonym |
neuroendocrine tumour G1 carcinoid tumour (disease) neuroendocrine neoplasm G1 carcinoid tumor (disease) carcinoid tumor neuroendocrine tumor G1 NET G1 carcinoid |
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| IAO_0000115 |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. |
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| IAO_0000589 |
carcinoid tumor (disease) |
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| id |
MONDO:0005369 |
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| inSubset | ||
| label |
carcinoid tumor |
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| notation |
MONDO:0005369 |
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| prefLabel |
carcinoid tumor |
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| subClassOf |