loading...| Preferred Name |
nuclease |
|
| Synonyms |
site-specific DNA nuclease |
|
| Definitions |
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome. |
|
| ID |
http://purl.obolibrary.org/obo/FBcv_0005077 |
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| contributor | ||
| date |
2017-12-13T13:17:30Z |
|
| definition |
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome. |
|
| has_obo_namespace |
experimental_tool_descriptor |
|
| has_related_synonym |
site-specific DNA nuclease |
|
| id |
FBcv:0005077 |
|
| in_subset | ||
| label |
nuclease |
|
| notation |
FBcv:0005077 |
|
| prefLabel |
nuclease |
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| subClassOf |