loading...| Preferred Name | Succimer | |
| Synonyms |
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|
| Definitions |
An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61953 |
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| CAS_Registry |
304-55-2 |
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| CHEBI_ID |
CHEBI:63623 |
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| Chemical_Formula |
C4H6O4S2 |
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| code |
C61953 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210. |
|
| Display_Name |
Succimer |
|
| FDA_UNII_Code |
DX1U2629QE |
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| FULL_SYN |
Butanedioic Acid, 2,3-Dimercapto-, (2R,3S)-rel- Meso 2, 3-Dimercaptosuccinic Acid Chemet DMSA SUCCIMER Succimer |
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| label |
Succimer |
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| Legacy Concept Name |
Succimer |
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| NCI_Drug_Dictionary_ID |
798947 |
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| PDQ_Closed_Trial_Search_ID |
798947 |
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| PDQ_Open_Trial_Search_ID |
798947 |
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| Preferred_Name |
Succimer |
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| prefixIRI |
Thesaurus:C61953 |
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| prefLabel |
Succimer |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0012384 |
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| 文本定义 |
An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210. |
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| subClassOf |