Epigenome Ontology

Last uploaded: July 3, 2016
Preferred Name

comet assay

Synonyms

SCGE assay

single cell gel electrophoresis assay

Definitions

a comet assay is an assay which utilizes gel electrophoresis on cell exposed to a challenge with the objective to assess DNA damage (DNA breakage) by determining the size and shape of DNA migration in cell placed in an electric field in specific conditions.

ID

http://purl.obolibrary.org/obo/OBI_0302736

achieves_planned_objective

http://purl.obolibrary.org/obo/OBI_0000441

alternative term

SCGE assay

single cell gel electrophoresis assay

definition

a comet assay is an assay which utilizes gel electrophoresis on cell exposed to a challenge with the objective to assess DNA damage (DNA breakage) by determining the size and shape of DNA migration in cell placed in an electric field in specific conditions.

definition source

PMID:7686265 .Mutat Res. 1993 Jul;288(1):47-63.The single cell gel electrophoresis assay (comet assay): a European review.

editor preferred term

comet assay

example of usage

PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay.

has curation status

http://purl.obolibrary.org/obo/IAO_0000122

has participant

http://purl.obolibrary.org/obo/OBI_0400140

http://purl.obolibrary.org/obo/OBI_0400142

http://purl.obolibrary.org/obo/CL_0000000

http://purl.obolibrary.org/obo/OBI_0000439

has_specified_input

http://purl.obolibrary.org/obo/CL_0000000

http://purl.obolibrary.org/obo/OBI_0000439

label

comet assay

prefixIRI

OBI:0302736

prefLabel

comet assay

term editor

Philippe Rocca-Serra

subClassOf

http://purl.obolibrary.org/obo/OBI_0000070

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