loading...| Preferred Name |
Hypereosinophilic syndrome |
|
| Synonyms |
eosinophilia Loeffler's Endocarditis hypereosinophilic syndrome hypereosinophilic disorder Idiopathic Hypereosinophilic Syndrome Loeffler Endocarditis eosinophilic leukocytosis hypereosinophilic disease HES |
|
| Definitions |
Hypereosinophilic syndrome (HES) constitutes a rare and heterogeneous group of disorders, defined as persistent and marked blood eosinophilia and/or tissue eosinophilia associated with a wide range of clinical manifestations reflecting eosinophil-induced tissue/organ damage. The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_1001467 |
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| closeMatch | ||
| database_cross_reference |
NCIT:C27038 Orphanet:168956 UMLS:C1540912 MedDRA:10048643 NANDO:2200806 NANDO:2200805 MESH:D017681 SCTID:419455006 ICDO:9964/3 ORDO:Orphanet_168956 MeSH:D017681 Wikipedia:Hypereosinophilic_syndrome DOID:999 GARD:2804 ICD9:288.3 MONDO:0015691 |
|
| definition |
Hypereosinophilic syndrome (HES) constitutes a rare and heterogeneous group of disorders, defined as persistent and marked blood eosinophilia and/or tissue eosinophilia associated with a wide range of clinical manifestations reflecting eosinophil-induced tissue/organ damage. The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out. |
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| disease has major feature | ||
| exactMatch |
http://purl.obolibrary.org/obo/DOID_999 http://linkedlifedata.com/resource/umls/id/C1540912 http://purl.obolibrary.org/obo/NCIT_C27038 http://identifiers.org/snomedct/419455006 |
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| has_exact_synonym |
Loeffler's Endocarditis hypereosinophilic syndrome hypereosinophilic disorder Idiopathic Hypereosinophilic Syndrome Loeffler Endocarditis eosinophilic leukocytosis hypereosinophilic disease HES |
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| has_related_synonym |
eosinophilia |
|
| id |
EFO:1001467 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders http://purl.obolibrary.org/obo/mondo/mondo-base#disease_grouping |
|
| label |
Hypereosinophilic syndrome |
|
| notation |
EFO:1001467 |
|
| preferred label |
Hypereosinophilic syndrome |
|
| prefLabel |
Hypereosinophilic syndrome |
|
| term editor |
Gautier Koscielny |
|
| subClassOf |
http://www.orpha.net/ORDO/Orphanet_158300 http://purl.obolibrary.org/obo/MONDO_0044972 |