Experimental Factor Ontology

Last uploaded: September 16, 2024
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Preferred Name

severe cutaneous adverse reaction
Synonyms

severe cutaneous adverse reaction

SCAR

Scar
Definitions

Group of severe, sometimes life-threatening skin reactions that are often drug-induced. Severe cutaneous adverse reactions (SCARs) include: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis. A group of skin disorders including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE).
ID

http://www.ebi.ac.uk/efo/EFO_0006346
closeMatch

http://identifiers.org/meddra/20000020
database_cross_reference

NCIt:C34483

UMLS:C5554042

MedDRA:20000020

SNOMEDCT:12402003

MONDO:0005594

SNOMEDCT:275322007

MEDGEN:1843455
definition

Group of severe, sometimes life-threatening skin reactions that are often drug-induced. Severe cutaneous adverse reactions (SCARs) include: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis.

A group of skin disorders including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE).
exactMatch

http://identifiers.org/medgen/1843455

http://linkedlifedata.com/resource/umls/id/C5554042
gwas_trait

true
has_exact_synonym

severe cutaneous adverse reaction

SCAR

Scar
IAO_0000233

https://github.com/monarch-initiative/mondo/issues/7258
id

EFO:0006346
in_subset

http://purl.obolibrary.org/obo/mondo#otar
label

severe cutaneous adverse reaction
notation

EFO:0006346
preferred label

severe cutaneous adverse reaction
prefLabel

severe cutaneous adverse reaction
term editor

Dani Welter
subClassOf

http://www.ebi.ac.uk/efo/EFO_0000701
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