Experimental Factor Ontology

Last uploaded: October 15, 2024
Preferred Name

LNCaP clone FGC
Synonyms

LNCaP clone FGC cell

CRL-1740

LNCaP-FGC

LNCaP_FGC

Definitions

LNCaP clone FGC was isolated in 1977 by J.S. Horoszewicz, et al., from a needle aspiration biopsy of the left supraclavicular lymph node of a 50-year-old Caucasian male (blood type B+) with confirmed diagnosis of metastatic prostate carcinoma. This is a hypotetraploid human cell line. The modal chromosome number was 84, occurring in 22% of cells. However, cells with chromosome counts of 86 (20%) and 87 (18%) also occurred at high frequencies. These cells are responsive to 5-alpha-dihydrotestosterone (growth modulation and acid phosphatase production).

ID

http://www.ebi.ac.uk/efo/EFO_0005726

database_cross_reference

PMID:2660395

definition

LNCaP clone FGC was isolated in 1977 by J.S. Horoszewicz, et al., from a needle aspiration biopsy of the left supraclavicular lymph node of a 50-year-old Caucasian male (blood type B+) with confirmed diagnosis of metastatic prostate carcinoma. This is a hypotetraploid human cell line. The modal chromosome number was 84, occurring in 22% of cells. However, cells with chromosome counts of 86 (20%) and 87 (18%) also occurred at high frequencies. These cells are responsive to 5-alpha-dihydrotestosterone (growth modulation and acid phosphatase production).

has characteristic

http://www.ebi.ac.uk/efo/EFO_0000196

http://purl.obolibrary.org/obo/PATO_0000384

has quality

http://purl.obolibrary.org/obo/PATO_0000384

has_exact_synonym

LNCaP clone FGC cell

CRL-1740

LNCaP-FGC

LNCaP_FGC

label

LNCaP clone FGC

part_of

http://purl.obolibrary.org/obo/HANCESTRO_0005

preferred label

LNCaP clone FGC

prefixIRI

efo:EFO_0005726

prefLabel

LNCaP clone FGC

treeView

http://purl.obolibrary.org/obo/HANCESTRO_0005

subClassOf

http://www.ebi.ac.uk/efo/EFO_0001641

http://www.ebi.ac.uk/efo/EFO_0002891

http://www.ebi.ac.uk/efo/EFO_0002888

http://purl.obolibrary.org/obo/BTO_0001033

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