loading...| Preferred Name |
acute lung injury |
|
| Synonyms |
acute lung injury ALI |
|
| Definitions |
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (pulmonary edema) rich in neutrophils, and in the absence of clinical heart failure. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). Acute lung injury (ALI) is a diffuse heterogeneous lung injury characterized by hypoxemia, non cardiogenic pulmonary edema, low lung compliance and widespread capillary leakage. ALI is caused by any stimulus of local or systemic inflammation, principally sepsis. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0004610 |
|
| closeMatch | ||
| database_cross_reference |
MedDRA:10069351 Orphanet:178320 MESH:D055371 SNOMEDCT:315345002 MeSH:D055371 NCIT:C155766 SCTID:315345002 GARD:20146 MONDO:0015796 |
|
| definition |
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (pulmonary edema) rich in neutrophils, and in the absence of clinical heart failure. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). Acute lung injury (ALI) is a diffuse heterogeneous lung injury characterized by hypoxemia, non cardiogenic pulmonary edema, low lung compliance and widespread capillary leakage. ALI is caused by any stimulus of local or systemic inflammation, principally sepsis. |
|
| definition_citation | ||
| exactMatch |
http://identifiers.org/snomedct/315345002 http://purl.obolibrary.org/obo/Orphanet_178320 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
acute lung injury ALI |
|
| id |
EFO:0004610 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_clinical_situation http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disease |
|
| label |
acute lung injury |
|
| notation |
EFO:0004610 |
|
| prefLabel |
acute lung injury |
|
| term editor |
Helen Parkinson |
|
| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000546 |