loading...| Preferred Name | bundle branch block | |
| Synonyms |
bundle-branch block |
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| Definitions |
A bundle branch block refers to a defect of the heart's electrical conduction system in which the bundle branch may cease to conduct electrical impulses appropriately. This results in altered pathways for ventricular depolarization. Since the electrical impulse can no longer use the preferred pathway across the bundle branch, it may move instead through muscle fibers in a way that both slows the electrical movement and changes the directional propagation of the impulses. As a result, there is a loss of ventricular synchrony, ventricular depolarization is prolonged, and there may be a corresponding drop in cardiac output. When heart failure is present, a specialized pacemaker may be used to resynchronize the ventricles |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0004138 |
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| database_cross_reference |
MedDRA:10006583 MedDRA:10006584 MeSH:D002037 MedDRA:10006578 SNOMEDCT:6374002 OMIM:113900 ICD10:I44 |
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| definition |
A bundle branch block refers to a defect of the heart's electrical conduction system in which the bundle branch may cease to conduct electrical impulses appropriately. This results in altered pathways for ventricular depolarization. Since the electrical impulse can no longer use the preferred pathway across the bundle branch, it may move instead through muscle fibers in a way that both slows the electrical movement and changes the directional propagation of the impulses. As a result, there is a loss of ventricular synchrony, ventricular depolarization is prolonged, and there may be a corresponding drop in cardiac output. When heart failure is present, a specialized pacemaker may be used to resynchronize the ventricles |
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| definition_citation |
derived from wikipedia http://en.wikipedia.org/wiki/Bundle_branch_block |
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| gwas_trait |
true |
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| has_exact_synonym |
bundle-branch block |
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| label |
bundle branch block |
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| preferred label |
bundle branch block |
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| prefixIRI |
efo:EFO_0004138 |
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| prefLabel |
bundle branch block |
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| term editor |
James Malone |
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| subClassOf |