loading...| Preferred Name |
monocyte |
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| Synonyms |
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| Definitions |
Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. |
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| ID |
http://purl.obolibrary.org/obo/CL_0000576 |
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| comment |
Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. |
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| database_cross_reference |
SNOMEDCT:55918008 MeSH:D009000 NCIt:C12547 BTO:0000876 CALOHA:TS-0638 FMA:62864 |
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| definition |
Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim |
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| label |
monocyte |
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| located_in | ||
| preferred label |
monocyte |
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| prefixIRI |
CL:0000576 |
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| prefLabel |
monocyte |
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| RO_0002175 | ||
| subClassOf |
http://purl.obolibrary.org/obo/CL_0000842 |