loading...| Preferred Name |
pazopanib |
|
| Synonyms |
GW786034 GW 78603 pazopanibum pazopanib 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide |
|
| Definitions |
A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_71219 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:22759480 PMID:23088634 PMID:22341567 LINCS:LSM-1114 PMID:23064954 PMID:22190407 PMID:21811833 PMID:23072642 PMID:23135778 PMID:22233389 PMID:22984765 Patent:US2008293691 PMID:22733110 Reaxys:11646488 Patent:WO2007064753 PMID:22917595 Patent:WO2011058179 Drug_Central:4118 Wikipedia:Pazopanib Patent:WO2011150044 Patent:WO2007143483 CAS:444731-52-6 PMID:22112314 Patent:WO2011069053 PMID:22716487 PMID:22766517 PMID:22359392 PMID:22830347 PMID:22595799 Patent:WO2012106302 PMID:23054212 Patent:WO2006020564 PMID:21766486 PMID:22733795 PMID:21394443 PMID:22679111 PMID:22688250 PMID:22861374 |
|
| definition |
A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. |
|
| formula |
C21H23N7O2S |
|
| has_exact_synonym |
5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
GW786034 GW 78603 pazopanibum pazopanib |
|
| id |
CHEBI:71219 |
|
| in_subset | ||
| inchi |
InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25) |
|
| inchikey |
CUIHSIWYWATEQL-UHFFFAOYSA-N |
|
| label |
pazopanib |
|
| mass |
437.520 |
|
| monoisotopicmass |
437.16339 |
|
| notation |
CHEBI:71219 |
|
| preferred label |
pazopanib |
|
| prefLabel |
pazopanib |
|
| smiles |
C1=C(C(=CC(=C1)NC=2N=CC=C(N2)N(C=3C=CC=4C(C3)=NN(C4C)C)C)S(N)(=O)=O)C |
|
| subClassOf |