The Drug Ontology

Last uploaded: December 20, 2024
Preferred Name

torasemide
Synonyms

N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea

N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide

torasemidum

AC 4464

AC-4464

AC4464

BM 02015

BM-02.015

BM-02015

BM02.015

BM02015

Demadex

JDL 464

JDL-464

Luprac

Torem

Torsemide

Unat

torasemida

torasemide

4-(3-methylanilino)-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide

Definitions

An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.

ID

http://purl.obolibrary.org/obo/CHEBI_9637

alternative label

N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea

N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide

torasemidum

AC 4464

AC-4464

AC4464

BM 02015

BM-02.015

BM-02015

BM02.015

BM02015

Demadex

JDL 464

JDL-464

Luprac

Torem

Torsemide

Unat

torasemida

torasemide

4-(3-methylanilino)-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide

charge

0

database_cross_reference

Drug_Central:2708

PMID:31124957

PMID:24040049

PMID:24243991

PMID:31809955

PMID:32098657

PMID:23877845

KEGG:D00382

PMID:22364690

DrugBank:DB00214

LINCS:LSM-2662

PMID:23013124

PMID:23792294

PMID:21391491

PMID:31699358

PMID:22030290

PMID:31436024

PMID:24432564

PMID:30649675

PMID:28891228

HMDB:HMDB0014359

PMID:29488197

PMID:32302808

Reaxys:498515

PMID:30827731

CAS:56211-40-6

PMID:23837587

PMID:24554915

PMID:24367917

PMID:32411731

Wikipedia:Torasemide

PMID:22407343

PMID:23237447

PMID:21906812

definition

An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.

formula

C16H20N4O3S

has characteristic

http://purl.obolibrary.org/obo/CHEBI_77608

http://purl.obolibrary.org/obo/CHEBI_35674

has functional parent

http://purl.obolibrary.org/obo/CHEBI_34385

has role

http://purl.obolibrary.org/obo/CHEBI_77608

http://purl.obolibrary.org/obo/CHEBI_35674

has_exact_synonym

4-(3-methylanilino)-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide

has_obo_namespace

chebi_ontology

has_related_synonym

N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide

1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea

N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide

torasemidum

AC 4464

AC-4464

AC4464

BM 02015

BM-02.015

BM-02015

BM02.015

BM02015

Demadex

JDL 464

JDL-464

Luprac

Torem

Torsemide

Unat

torasemida

torasemide

has_RxCUI

38413

id

CHEBI:9637

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

inchikey

NGBFQHCMQULJNZ-UHFFFAOYSA-N

label

torasemide

mass

348.420

monoisotopicmass

348.12561

notation

CHEBI:9637

prefLabel

torasemide

smiles

C=1(C(NC=2C=C(C=CC2)C)=CC=NC1)S(NC(NC(C)C)=O)(=O)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_50995

http://purl.obolibrary.org/obo/CHEBI_76983

http://purl.obolibrary.org/obo/CHEBI_38207

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