loading...| Preferred Name | oxamniquine | |
| Synonyms |
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol (+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol rac-oxamniquine rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline oxamniquina oxamniquine rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol oxamniquinum Mansil UK 4271 UK-4271 UK4271 Vansil rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol |
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| Definitions |
A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_7819 |
|
| alternative label |
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol (+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol rac-oxamniquine rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline oxamniquina oxamniquine rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol oxamniquinum Mansil UK 4271 UK-4271 UK4271 Vansil rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol |
|
| charge |
0 |
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| database_cross_reference |
PMID:4977703 PMID:349665 PMID:2638729 PMID:8839672 Reaxys:485597 PMID:23450530 PMID:11516919 DrugBank:DB01096 KEGG:C07341 PMID:3127959 PMID:734715 PMID:2083150 KEGG:D00460 PMID:10321028 PDBeChem:OAQ PMID:4203813 PMID:21500322 CAS:21738-42-1 PMID:7767464 PMID:17988075 PMID:3082231 Patent:US3821228 PMID:823880 Wikipedia:Oxamniquine PMID:4205106 PMID:2490562 HMDB:HMDB0015228 PMID:1198006 |
|
| definition |
A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site. |
|
| formula |
C14H21N3O3 |
|
| has part | ||
| has role | ||
| has_exact_synonym |
rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline (+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol (+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol rac-oxamniquine rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline oxamniquina oxamniquine rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol oxamniquinum Mansil UK 4271 UK-4271 UK4271 Vansil |
|
| has_RxCUI |
7778 |
|
| id |
CHEBI:7819 |
|
| in_subset | ||
| label |
oxamniquine |
|
| mass |
279.33480 |
|
| monoisotopicmass |
279.15829 |
|
| notation |
CHEBI:7819 |
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| prefLabel |
oxamniquine |
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| subClassOf |