Preferred Name |
perampanel |
|
Synonyms |
2-(6'-oxo-1'-phenyl-1',6'-dihydro-2,3'-bipyridin-5'-yl)benzonitrile ER-155055-90 perampanelum 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one E 2007 E2007 Fycompa perampanel |
|
Definitions |
A member of the class of bipyridines that is 2,3'-bipyridin-6'-one substituted at positions 1' and 5' by phenyl and 2-cyanophenyl groups respectively. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_71013 |
|
charge |
0 |
|
database_cross_reference |
Patent:US2009088574 PMID:22222634 Patent:EP1875912 Wikipedia:Perampanel PMID:21635236 PMID:21883097 PMID:22913800 PMID:22161845 PMID:22843280 PMID:22433907 CAS:380917-97-5 PMID:22517103 PMID:22776828 Reaxys:11343244 Patent:US2008108603 Drug_Central:4684 Patent:WO2008111590 PMID:22905878 PMID:22650169 PMID:23093905 PMID:21686307 KEGG:D08964 PMID:22905857 PMID:23114872 Patent:WO2006107859 PMID:22788917 |
|
definition |
A member of the class of bipyridines that is 2,3'-bipyridin-6'-one substituted at positions 1' and 5' by phenyl and 2-cyanophenyl groups respectively. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy. |
|
formula |
C23H15N3O |
|
has functional parent | ||
has role | ||
has_exact_synonym |
2-(6'-oxo-1'-phenyl-1',6'-dihydro-2,3'-bipyridin-5'-yl)benzonitrile |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
ER-155055-90 perampanelum 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one E 2007 E2007 Fycompa perampanel |
|
has_RxCUI |
1356552 |
|
id |
CHEBI:71013 |
|
in_subset | ||
inchi |
InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H |
|
inchikey |
PRMWGUBFXWROHD-UHFFFAOYSA-N |
|
label |
perampanel |
|
mass |
349.38470 |
|
monoisotopicmass |
349.12151 |
|
notation |
CHEBI:71013 |
|
prefLabel |
perampanel |
|
smiles |
O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N |
|
subClassOf |
http://purl.obolibrary.org/obo/CHEBI_38183 |