loading...| Preferred Name |
latanoprost |
|
| Synonyms |
latanoprost isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate latanoprostum PhXA 41 Xalatan isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate |
|
| Definitions |
A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6384 |
|
| alternative label |
latanoprost isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate latanoprostum PhXA 41 Xalatan isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate |
|
| charge |
0 |
|
| database_cross_reference |
PMID:22167539 PMID:22167538 PMID:22275828 Drug_Central:1551 PMID:22275814 Wikipedia:Latanoprost DrugBank:DB00654 PMID:22320418 PMID:22283238 PMID:22049909 Beilstein:5912370 PMID:22040280 HMDB:HMDB0014792 Reaxys:5912370 PMID:21278589 PMID:21858678 KEGG:D00356 PMID:22323882 PMID:22289196 PMID:22289195 CAS:130209-82-4 |
|
| definition |
A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension. |
|
| formula |
C26H40O5 |
|
| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_39456 http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| has_exact_synonym |
isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
latanoprost isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate latanoprostum PhXA 41 Xalatan |
|
| has_RxCUI |
43611 |
|
| id |
CHEBI:6384 |
|
| in_subset | ||
| inchi |
InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1 |
|
| inchikey |
GGXICVAJURFBLW-CEYXHVGTSA-N |
|
| label |
latanoprost |
|
| mass |
432.59280 |
|
| monoisotopicmass |
432.28757 |
|
| notation |
CHEBI:6384 |
|
| prefLabel |
latanoprost |
|
| smiles |
CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc1ccccc1 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35725 |