The Drug Ontology

Last uploaded: November 15, 2024
Preferred Name

chlorpropamide
Synonyms

clorpropamida

1-propyl-3-(p-chlorobenzenesulfonyl)urea

1-(p-chlorophenylsulfonyl)-3-propylurea

1-(p-chlorobenzenesulfonyl)-3-propylurea

N-(4-chlorophenylsulfonyl)-N'-propylurea

n-propyl-N'-p-chlorophenylsulfonylcarbamide

4-chloro-N-((propylamino)carbonyl)benzenesulfonamide

chlorpropamide

n-propyl-N'-(p-chlorobenzenesulfonyl)urea

4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide

N-(p-chlorobenzenesulfonyl)-N'-propylurea

chlorpropamidum

CHLORPROPAMIDE

Definitions

An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

ID

http://purl.obolibrary.org/obo/CHEBI_3650

alternative label

clorpropamida

1-propyl-3-(p-chlorobenzenesulfonyl)urea

1-(p-chlorophenylsulfonyl)-3-propylurea

1-(p-chlorobenzenesulfonyl)-3-propylurea

N-(4-chlorophenylsulfonyl)-N'-propylurea

n-propyl-N'-p-chlorophenylsulfonylcarbamide

4-chloro-N-((propylamino)carbonyl)benzenesulfonamide

chlorpropamide

n-propyl-N'-(p-chlorobenzenesulfonyl)urea

4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide

N-(p-chlorobenzenesulfonyl)-N'-propylurea

chlorpropamidum

CHLORPROPAMIDE

charge

0

database_cross_reference

DrugBank:DB00672

Wikipedia:Chlorpropamide

LINCS:LSM-6695

PMID:2657066

KEGG:D00271

PMID:3806586

Reaxys:2218363

Drug_Central:622

PMID:10891117

Patent:US3349124

HMDB:HMDB0014810

Beilstein:2218363

CAS:94-20-2

Patent:GB853555

definition

An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

formula

C10H13ClN2O3S

has role

http://purl.obolibrary.org/obo/CHEBI_35526

http://purl.obolibrary.org/obo/CHEBI_90415

has_alternative_id

CHEBI:108516

has_exact_synonym

CHLORPROPAMIDE

has_obo_namespace

chebi_ontology

has_related_synonym

clorpropamida

1-propyl-3-(p-chlorobenzenesulfonyl)urea

1-(p-chlorophenylsulfonyl)-3-propylurea

1-(p-chlorobenzenesulfonyl)-3-propylurea

N-(4-chlorophenylsulfonyl)-N'-propylurea

n-propyl-N'-p-chlorophenylsulfonylcarbamide

4-chloro-N-((propylamino)carbonyl)benzenesulfonamide

chlorpropamide

n-propyl-N'-(p-chlorobenzenesulfonyl)urea

4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide

N-(p-chlorobenzenesulfonyl)-N'-propylurea

chlorpropamidum

has_RxCUI

2404

id

CHEBI:3650

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

inchikey

RKWGIWYCVPQPMF-UHFFFAOYSA-N

label

chlorpropamide

mass

276.74000

monoisotopicmass

276.03354

notation

CHEBI:3650

prefLabel

chlorpropamide

smiles

CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_83403

http://purl.obolibrary.org/obo/CHEBI_76983

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http://purl.obolibrary.org/obo/CHEBI_3650 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3650 CHEBI SAME_URI
http://sbmi.uth.tmc.edu/ontology/ochv#2843 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 EFO LOOM
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http://purl.obolibrary.org/obo/CHEBI_3650 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3650 CHEBI LOOM
http://purl.bioontology.org/ontology/RXNORM/2404 RXNORM LOOM
http://purl.bioontology.org/ontology/SNMI/C-A2420 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/000910 NDDF LOOM
http://purl.jp/bio/4/id/200906059002633990 IOBC LOOM
http://stirdf.jst.go.jp/id/200907040391409112 IOBC LOOM
http://www.drugbank.ca/drugs/DB00672 FTC LOOM
http://purl.obolibrary.org/obo/MESH_D002747 BERO LOOM
http://purl.bioontology.org/ontology/RCD/f32.. RCD LOOM
http://purl.obolibrary.org/obo/XCO_0001144 XCO LOOM
http://purl.bioontology.org/ontology/LNC/LP16075-1 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062942 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002747 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C47447 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008287 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4017841 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386991003 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB00672 MDM LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000775373 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.948.828.283 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Chlorpropamide GALEN LOOM
http://purl.obolibrary.org/obo/OMIT_0004068 OMIT LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#chlorpropamide SDO LOOM
http://purl.bioontology.org/ontology/ATC/A10BB02 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D002747 MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47447 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.795.283 RH-MESH LOOM
rgo:15222 GAMUTS LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017436 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146198 NDFRT LOOM