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The Drug Ontology
Last uploaded:
December 20, 2024
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| Preferred Name | cerivastatin sodium | |
| Synonyms |
(+)-sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate |
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| Definitions |
The sodium salt of cerivastatin. Formerly used to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_3559 |
|
| alternative label |
(+)-sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate
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|
| charge |
0
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|
| database_cross_reference |
CAS:143201-11-0 DrugBank:DB00439 Beilstein:8466341 KEGG:D00889 Patent:US5177080
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|
| definition |
The sodium salt of cerivastatin. Formerly used to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
|
|
| formula |
C26H33FNNaO5
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|
| has part | ||
| has_exact_synonym |
sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate
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|
| has_obo_namespace |
chebi_ontology
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|
| has_related_synonym |
(+)-sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate
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|
| has_RxCUI |
221072
|
|
| id |
CHEBI:3559
|
|
| in_subset | ||
| inchi |
InChI=1S/C26H34FNO5.Na/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4;/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32);/q;+1/p-1/b11-10+;/t19-,20-;/m1./s1
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|
| inchikey |
GPUADMRJQVPIAS-QCVDVZFFSA-M
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|
| label |
cerivastatin sodium
|
|
| mass |
481.53210
|
|
| monoisotopicmass |
481.22405
|
|
| notation |
CHEBI:3559
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|
| prefLabel |
cerivastatin sodium
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| smiles |
[Na+].COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(C)C
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| subClassOf |
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