The Drug Ontology

Last uploaded: November 15, 2024
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Preferred Name

cefuroxime
Synonyms

Zinacef Danmark

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cephuroxime

cefuroximum

Cefuroxim

Sharox

cefuroxime

cefuroximo

3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid

Cefuroxime
Definitions

A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
ID

http://purl.obolibrary.org/obo/CHEBI_3515
alternative label

Zinacef Danmark

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cephuroxime

cefuroximum

Cefuroxim

Sharox

cefuroxime

cefuroximo

3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid

Cefuroxime
charge

0
database_cross_reference

DrugBank:DB01112

PMID:18795089

PMID:12898829

PMID:19142482

Patent:US4267320

PMID:11581233

PMID:18208759

Patent:DE2439880

PMID:15052582

MetaCyc:CPD0-2069

PMID:17113884

PMID:12833570

PMID:17261579

KEGG:D00262

PMID:12235459

PMID:14658923

KEGG:C06894

Patent:DE2706413

Drug_Central:565

PMID:17676080

PMID:11322179

PMID:15828440

PMID:29017833

PMID:16341950

PMID:19069618

Patent:US3974153

PMID:11168076

PMID:12141712

PMID:17366015

CAS:55268-75-2

PMID:19411164

PMID:18931469

Wikipedia:Cefuroxime

Reaxys:5783190

PMID:18611587

PMID:17111749

PMID:21425867
definition

A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
formula

C16H16N4O8S
has_exact_synonym

3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid

Cefuroxime
has_obo_namespace

chebi_ontology
has_related_synonym

Zinacef Danmark

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cephuroxime

cefuroximum

Cefuroxim

Sharox

cefuroxime

cefuroximo
has_RxCUI

2194
id

CHEBI:3515
in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR
inchi

InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1
inchikey

JFPVXVDWJQMJEE-IZRZKJBUSA-N
label

cefuroxime
mass

424.38640
monoisotopicmass

424.06888
notation

CHEBI:3515
prefLabel

cefuroxime
smiles

[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1ccco1)C(O)=O
subClassOf

http://purl.obolibrary.org/obo/CHEBI_24129

http://purl.obolibrary.org/obo/CHEBI_36816

http://purl.obolibrary.org/obo/CHEBI_28084
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3515 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 DOID SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3515 EFO SAME_URI
http://purl.obolibrary.org/obo/ARO_0000063 ARO LOOM
https://go.drugbank.com/drugs/DB01112 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61669 NCIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147760 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4019668 VANDF LOOM
http://purl.obolibrary.org/obo/XCO_0001088 XCO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372833007 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002444 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0003774 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/S01AA27 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.190.190.165 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Cefuroxime GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.190.190.165 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB01112 DINTO LOOM
http://purl.jp/bio/4/id/200906082611500095 IOBC LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cefuroxime SEPON LOOM
http://purl.bioontology.org/ontology/LNC/MTHU027952 LOINC LOOM
http://purl.obolibrary.org/obo/ARO_0000063 ARO LOOM
http://purl.obolibrary.org/obo/NCIT_C61669 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015887 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0007562 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D002444 BERO LOOM
http://purl.bioontology.org/ontology/ATC/J01DC02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP32648-5 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2572 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D002444 MESH LOOM
http://stirdf.jst.go.jp/id/200907032419857059 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-53360 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 EFO LOOM
http://purl.bioontology.org/ontology/RXNORM/2194 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.190.190.165 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/e68.. RCD LOOM