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The Drug Ontology
Last uploaded:
December 20, 2024
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| Preferred Name | cefpodoxime | |
| Synonyms |
cefpodoximum cefpodoxima cefpodoxime (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid |
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| Definitions |
A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3504 |
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| alternative label |
cefpodoximum cefpodoxima cefpodoxime (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
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|
| charge |
0
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| database_cross_reference |
PMID:21395603 KEGG:D07650 KEGG:C08114 PMID:20821175 PMID:21569093 Wikipedia:Cefpodoxime PMID:21509928 CAS:80210-62-4 DrugBank:DB01416 PMID:21667000 PMID:29017833 PMID:20606336 Reaxys:6021381 PMID:21455420 PMID:21420838 VSDB:2968
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|
| definition |
A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
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|
| formula |
C15H17N5O6S2
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| has characteristic | ||
| has role | ||
| has_alternative_id |
CHEBI:606443
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| has_exact_synonym |
7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
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| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
cefpodoximum cefpodoxima cefpodoxime (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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|
| has_RxCUI |
20489
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|
| id |
CHEBI:3504
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| in_subset | ||
| inchi |
InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
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| inchikey |
WYUSVOMTXWRGEK-HBWVYFAYSA-N
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|
| label |
cefpodoxime
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|
| mass |
427.45500
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|
| monoisotopicmass |
427.06203
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| notation |
CHEBI:3504
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| prefLabel |
cefpodoxime
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| smiles |
[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
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| subClassOf |
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