Link to this page
The Drug Ontology
| Preferred Name | tolvaptan | |
| Synonyms |
N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (+-)-tolvaptan (+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide (RS)-tolvaptan tolvaptanum RS-tolvaptan Jinarc Jynarque OPC 41061 OPC-41061 Samsca tolvaptan rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide |
|
| Definitions |
A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_32246 |
|
| alternative label |
N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (+-)-tolvaptan (+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide (RS)-tolvaptan tolvaptanum RS-tolvaptan Jinarc Jynarque OPC 41061 OPC-41061 Samsca tolvaptan rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
|
|
| charge |
0
|
|
| database_cross_reference |
PMID:38606040 PMID:38097698 PMID:37587049 PMID:38652561 PMID:37916285 PMID:34386666 PMID:38423003 PMID:12742979 PMID:34476570 PMID:38512373 Drug_Central:4110 PMID:34526469 PMID:38616432 PMID:38396765 PMID:38288467 DrugBank:DB06212 PMID:38509003 PMID:37516894 PMID:38562967 PMID:37214762 PMID:38577748 PMID:38608748 PMID:38344178 PMID:16211205 PMID:38710808 KEGG:D01213 PMID:38468548 PMID:34514204 PMID:38414126 PMID:37845144 PMID:33078835 PMID:38717378 PMID:38337413 Wikipedia:Tolvaptan PMID:37982946 PMID:37845430 PMID:34554640 PMID:38494546 CAS:150683-30-0 PMID:37466863 PMID:34070416
|
|
| definition |
A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency.
|
|
| formula |
C26H25ClN2O3
|
|
| has characteristic | ||
| has part | ||
| has role | ||
| has_exact_synonym |
rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (+-)-tolvaptan (+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide (RS)-tolvaptan tolvaptanum RS-tolvaptan Jinarc Jynarque OPC 41061 OPC-41061 Samsca tolvaptan
|
|
| has_RxCUI |
358257
|
|
| id |
CHEBI:32246
|
|
| in_subset | ||
| label |
tolvaptan
|
|
| mass |
448.950
|
|
| monoisotopicmass |
448.15537
|
|
| notation |
CHEBI:32246
|
|
| prefLabel |
tolvaptan
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |