Link to this page
The Drug Ontology
Last uploaded:
December 20, 2024
Jump to:
| Preferred Name | droxidopa | |
| Synonyms |
L-Threodops (2S,3R)-3,4-dihydroxy-phenylserine (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid L-Dihydroxyphenylserine L-threo-dihydroxyphenylserine threo-Dopaserine Dops Droxydopa L-DOPS Northera SM 5688 droxidopa droxidopum (betaR)-beta,3-dihydroxy-L-tyrosine |
|
| Definitions |
A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_31524 |
|
| alternative label |
L-Threodops (2S,3R)-3,4-dihydroxy-phenylserine (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid L-Dihydroxyphenylserine L-threo-dihydroxyphenylserine threo-Dopaserine Dops Droxydopa L-DOPS Northera SM 5688 droxidopa droxidopum (betaR)-beta,3-dihydroxy-L-tyrosine
|
|
| charge |
0
|
|
| database_cross_reference |
HMDB:HMDB0015627 PMID:24326693 PMID:24224390 PMID:24883005 Patent:US2012010293 Patent:JP2005247828 DrugBank:DB06262 PMID:22610782 Patent:US2013253061 PMID:20207766 Patent:US2008221170 PMID:24944260 PMID:24517276 Reaxys:7112431 KEGG:D01277 Drug_Central:971 PMID:24958960 PMID:20220040 PMID:24644107 PMID:23224983 CAS:23651-95-8 PMID:11710796 PMID:22561478 PMID:24729712 Wikipedia:Droxidopa Patent:NZ579368 PMID:20063034 PMID:21705113
|
|
| definition |
A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension
|
|
| formula |
C9H11NO5
|
|
| has characteristic |
http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| has_exact_synonym |
(betaR)-beta,3-dihydroxy-L-tyrosine
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
L-Threodops (2S,3R)-3,4-dihydroxy-phenylserine (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid L-Dihydroxyphenylserine L-threo-dihydroxyphenylserine threo-Dopaserine Dops Droxydopa L-DOPS Northera SM 5688 droxidopa droxidopum
|
|
| has_RxCUI |
1489913
|
|
| id |
CHEBI:31524
|
|
| in_subset | ||
| inchi |
InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
|
|
| inchikey |
QXWYKJLNLSIPIN-JGVFFNPUSA-N
|
|
| label |
droxidopa
|
|
| mass |
213.18730
|
|
| monoisotopicmass |
213.06372
|
|
| notation |
CHEBI:31524
|
|
| prefLabel |
droxidopa
|
|
| smiles |
N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping