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The Drug Ontology
| Preferred Name | betaxolol | |
| Synonyms |
betaxololum 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol betaxolol 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol |
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| Definitions |
A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_3082 |
|
| alternative label |
betaxololum 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol betaxolol 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
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|
| charge |
0
|
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| database_cross_reference |
PMID:2569884 HMDB:HMDB0014341 Patent:US4252984 PMID:14971904 PMID:15993593 Drug_Central:356 PMID:10891117 KEGG:D07526 LINCS:LSM-1255 Reaxys:1991268 Patent:DE2649605 PMID:1361581 PMID:1865331 DrugBank:DB00195 CAS:63659-18-7 KEGG:C06849 Wikipedia:Betaxolol
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|
| definition |
A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.
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|
| formula |
C18H29NO3
|
|
| has characteristic |
http://purl.obolibrary.org/obo/CHEBI_66991 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_66991 |
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| has_alternative_id |
CHEBI:101354
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|
| has_exact_synonym |
1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
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|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
betaxololum 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol betaxolol
|
|
| has_RxCUI |
1520
|
|
| id |
CHEBI:3082
|
|
| in_subset | ||
| inchi |
InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
|
|
| inchikey |
NWIUTZDMDHAVTP-UHFFFAOYSA-N
|
|
| label |
betaxolol
|
|
| mass |
307.42780
|
|
| monoisotopicmass |
307.21474
|
|
| notation |
CHEBI:3082
|
|
| prefLabel |
betaxolol
|
|
| smiles |
CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
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| subClassOf |
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