The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	triamcinolone
Synonyms	9alpha-fluoro-16alpha-hydroxyprednisolone 9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione triamcinolona (11beta,16alpha)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 11beta,16alpha,17alpha,21-tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione 9alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Fluoxyprednisolone triamcinolonum C21H27FO6 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one triamcinolone 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
ID	http://purl.obolibrary.org/obo/CHEBI_9667
activates	http://purl.obolibrary.org/obo/dinto_2874
AHFScode	84:06.00 52:08.08 68:04.00
ATCCode	R03BA06 R01AD11 D07XB02 S01BA05 C05AA12 H02AB08 A01AC01 D07AB09
binds	http://purl.obolibrary.org/obo/dinto_2146
CASRN	124-94-7
DBBrand	trymex kenalog-h triamcinlon nasacort hfa tristoject triderm triamcinolon trilone oralone kenalog-10 nasacort triatex cinolone aristocort a aristocort tablets volon orion adcortyl celeste omcilon sk-triamcinolone omicilon triacet tricortale triacort rodinolone azmacort triamcet kenalog-40 delphicort cinolone-t tri-nasal kenalog triam-tablinen flutex aristogel kenalog in orabase aristocort volon a fougera oracort kenacort-ag nasacort aq kenacort aristospan ledercort
DBname	triamcinolone
DBSynonym	triamcinolone diacetate fluoxyprednisolone triamcinolona [inn-spanish] fluoxiprednisolone tiamcinolonum [inn-latin] triamcinolonum [inn] triamcinalone triamcinolone acetonide triamcinolone hexacetonide
Definition	A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000879 http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000838 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001510 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000489 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0001744 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000560 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000359 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001280 http://purl.obolibrary.org/obo/OAE_0001397 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0001339 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000340 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000353 http://purl.obolibrary.org/obo/OAE_0001468 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0001461 http://purl.obolibrary.org/obo/OAE_0000312 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001529 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000469 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000344 http://purl.obolibrary.org/obo/OAE_0001276 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000329 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000336 http://purl.obolibrary.org/obo/OAE_0000421 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0000313 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001458 http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2874
has role	http://purl.obolibrary.org/obo/CHEBI_35472 http://purl.obolibrary.org/obo/CHEBI_50857
InChI	InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChIKey	InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N
induces	http://purl.obolibrary.org/obo/dinto_3568
inhibits	http://purl.obolibrary.org/obo/dinto_2116
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901
label	triamcinolone
prefixIRI	obo2:CHEBI_9667
prefLabel	triamcinolone
SMILES	[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Synonym	9alpha-fluoro-16alpha-hydroxyprednisolone 9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione triamcinolona (11beta,16alpha)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 11beta,16alpha,17alpha,21-tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione 9alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Fluoxyprednisolone triamcinolonum C21H27FO6 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one triamcinolone 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
xref	Drugs Product Database (DPD):2229540 Guide To Pharmacology:2870 Wikipedia:Triamcinolone Patent:WO2005028495 ChemSpider:29046 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/azm1044.shtml ChEMBL:481691 Reaxys:2341955 CiteXplore:23440982 Drugs.com:http://www.drugs.com/cdi/triamcinolone-spray.html PubChem Substance:46507950 CiteXplore:23562859 CiteXplore:23151875 DrugBank:DB00620 RxList:http://www.rxlist.com/cgi/generic/triamaer.htm CiteXplore:7509503 CiteXplore:23370580 CiteXplore:22846803 CiteXplore:23449717 National Drug Code Directory:0781-3243-75 CiteXplore:15305946 HMDB:HMDB14758 CiteXplore:23473287 CiteXplore:19668443 CiteXplore:23337526 PubChem Compound:31307 Wikipedia:http://en.wikipedia.org/wiki/Triamcinolone KEGG DRUG:D00385 CASRN:124-94-7 PharmGKB:PA451749 NIST Chemistry WebBook:124-94-7 IUPHAR:2870 CiteXplore:11583068
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_9667	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9667	ODNAE	SAME_URI
http://purl.bioontology.org/ontology/ATC/D07XB02	ATC	LOOM
http://purl.bioontology.org/ontology/CSP/0059-8561	CRISP	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_9667	ODNAE	LOOM
http://www.co-ode.org/ontologies/galen#Triamcinolone	GALEN	LOOM
http://purl.obolibrary.org/obo/OMIT_0015060	OMIT	LOOM
http://purl.bioontology.org/ontology/RCD/x02M6	RCD	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/116594009	SNOMEDCT	LOOM
https://go.drugbank.com/drugs/DB00620	MDM	LOOM
http://purl.obolibrary.org/obo/MESH_D014221	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.432.915	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C901	BERO	LOOM
http://www.drugbank.ca/drugs/DB00620	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12516	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014221	RH-MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C901	NCIT	LOOM
http://purl.bioontology.org/ontology/ATC/C05AA12	ATC	LOOM
http://purl.bioontology.org/ontology/ATC/D07AB09	ATC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU018764	LOINC	LOOM
http://purl.jp/bio/4/id/200906034622468890	IOBC	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000145980	ODAE	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018699	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/ATC/R01AD11	ATC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145980	NDFRT	LOOM
http://stirdf.jst.go.jp/id/200907059919141608	IOBC	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039275	PDQ	LOOM
http://purl.bioontology.org/ontology/ATC/S01BA05	ATC	LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00315	OCIMIDO	LOOM
http://purl.bioontology.org/ontology/ATC/H02AB08	ATC	LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00854	COID	LOOM
http://purl.bioontology.org/ontology/ATC/R03BA06	ATC	LOOM
http://purl.bioontology.org/ontology/MESH/D014221	MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040864	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/A01AC01	ATC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.908.891	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/10759	RXNORM	LOOM
http://purl.bioontology.org/ontology/LNC/LP35873-6	LOINC	LOOM
http://purl.bioontology.org/ontology/VANDF/4017599	VANDF	LOOM