loading...| Preferred Name |
dezocine |
|
| Synonyms |
(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol C16H23NO dezocine dezocina dezocinum (1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol (-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol Dezocine |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4474 |
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| activates | ||
| altId |
CHEBI:618361 |
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| ATCCode |
N02AX03 |
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| blocks | ||
| CASRN |
53648-55-8 |
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| DBBrand |
dalgan |
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| DBname |
dezocine |
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| DBSynonym |
dezocina [inn-spanish] dezocinum [inn-latin] |
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| Definition |
(7S,8S)-7-Amino-8-methyl-5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogen at position 8 and one of the hydrogens at position 6 are substituted by each end of a tetramethylene bridge. A synthetic opioid analgesic, it has mixed opiod agonist and antagonist properties. Although it is used for pain management, it can produce opioid withdrawal syndrome in patients already dependent on other opioids, and its clinical application is limited by side effects such as dizziness. |
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C16H23NO/c1-16-8-4-2-3-5-12(15(16)17)9-11-6-7-13(18)10-14(11)16/h6-7,10,12,15,18H,2-5,8-9,17H2,1H3/t12-,15-,16+/m0/s1 |
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| InChIKey |
InChIKey=VTMVHDZWSFQSQP-VBNZEHGJSA-N |
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| label |
dezocine |
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| may interact with | ||
| prefixIRI |
obo2:CHEBI_4474 |
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| prefLabel |
dezocine |
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| SMILES |
[H][C@@]12CCCCC[C@@](C)([C@H]1N)c1cc(O)ccc1C2 [H][C@@]12CC3=CC=C(O)C=C3[C@@](C)(CCCCC1)[C@H]2N |
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| Synonym |
(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol C16H23NO dezocine dezocina dezocinum (1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol (-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol Dezocine |
|
| xref |
CASRN:53648-55-8 DrugBank:DB01209 ChEBI:4474 PharmGKB:PA164746059 Patent:DE2159324 KEGG COMPOUND:C08010 Wikipedia:Dezocine KEGG DRUG:D00838 Beilstein:3033759 |
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| subClassOf |