The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

desvenlafaxine
Synonyms

4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol

C16H25NO2
ID

http://purl.obolibrary.org/obo/dinto_DB06700
AHFScode

28:16.04.16
ATCCode

N06AX23
binds

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_0901
CASRN

93413-62-8
DBBrand

zyven-od

pristiq
DBSalt

desvenlafaxine succinate
DBSynonym

o-desmethylvenlafaxine

odv
Definition

Desvenlafaxine (O-desmethylvenlafaxine) the major active metabolite of venlafaxine, is an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class). Desvenlafaxine may be used to treat major depressive disorder and is being studied for use in the management of vasomotor symptoms in postmenopausal women. It is formulated as an extended release tablet. FDA approved in 2008.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001045

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0000198

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000050

http://purl.obolibrary.org/obo/OAE_0000476

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001105

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0001200

http://purl.obolibrary.org/obo/OAE_0001295

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001164

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000394
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_0068
InChI

InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3
InChIKey

InChIKey=KYYIDSXMWOZKMP-UHFFFAOYSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_0068
is metabolised by

http://purl.obolibrary.org/obo/dinto_0901
is substrate of

http://purl.obolibrary.org/obo/dinto_0901
label

desvenlafaxine
may interact with

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_71417

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_36791

http://purl.obolibrary.org/obo/CHEBI_28918

http://purl.obolibrary.org/obo/dinto_DB01142

http://purl.obolibrary.org/obo/CHEBI_7936

http://purl.obolibrary.org/obo/CHEBI_3223

http://purl.obolibrary.org/obo/dinto_DB00476

http://purl.obolibrary.org/obo/dinto_DB00344

http://purl.obolibrary.org/obo/CHEBI_520985

http://purl.obolibrary.org/obo/CHEBI_34706

http://purl.obolibrary.org/obo/dinto_DB00540

http://purl.obolibrary.org/obo/dinto_DB01364

http://purl.obolibrary.org/obo/dinto_DB06706

http://purl.obolibrary.org/obo/CHEBI_47499

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/dinto_DB04896

http://purl.obolibrary.org/obo/CHEBI_47780

http://purl.obolibrary.org/obo/CHEBI_7494

http://purl.obolibrary.org/obo/CHEBI_3181

http://purl.obolibrary.org/obo/dinto_DB01323

http://purl.obolibrary.org/obo/CHEBI_48273

http://purl.obolibrary.org/obo/CHEBI_10650

http://purl.obolibrary.org/obo/CHEBI_7478

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/dinto_DB06204

http://purl.obolibrary.org/obo/dinto_DB00454

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00514

http://purl.obolibrary.org/obo/dinto_DB01356

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/CHEBI_51209

http://purl.obolibrary.org/obo/CHEBI_8461

http://purl.obolibrary.org/obo/CHEBI_3723

http://purl.obolibrary.org/obo/CHEBI_16828

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_63607

http://purl.obolibrary.org/obo/dinto_DB01171

http://purl.obolibrary.org/obo/dinto_DB01105

http://purl.obolibrary.org/obo/CHEBI_4646

http://purl.obolibrary.org/obo/CHEBI_9123

http://purl.obolibrary.org/obo/CHEBI_63620

http://purl.obolibrary.org/obo/CHEBI_6950

http://purl.obolibrary.org/obo/dinto_DB01037

http://purl.obolibrary.org/obo/dinto_DB00353

http://purl.obolibrary.org/obo/CHEBI_18357

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_4822

http://purl.obolibrary.org/obo/CHEBI_50922

http://purl.obolibrary.org/obo/CHEBI_47781

http://purl.obolibrary.org/obo/CHEBI_15414

http://purl.obolibrary.org/obo/dinto_DB06707

http://purl.obolibrary.org/obo/dinto_DB00998

http://purl.obolibrary.org/obo/dinto_DB00934

http://purl.obolibrary.org/obo/CHEBI_64318

http://purl.obolibrary.org/obo/CHEBI_2675

http://purl.obolibrary.org/obo/CHEBI_4562

http://purl.obolibrary.org/obo/CHEBI_2666

http://purl.obolibrary.org/obo/CHEBI_5118
prefixIRI

obo2:dinto_DB06700
prefLabel

desvenlafaxine
SMILES

CN(C)CC(C1=CC=C(O)C=C1)C1(O)CCCCC1
Synonym

4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol

C16H25NO2
xref

PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam

PharmGKB:PA165958374

National Drug Code Directory:0008-1211-14

PubChem Substance:99443254

PubChem Compound:125017

Wikipedia:http://en.wikipedia.org/wiki/Desvenlafaxine

Drugs Product Database (DPD):2321092

Drugs.com:http://www.drugs.com/ppa/desvenlafaxine-succinate.html

BindingDB:50010875

ChemSpider:111300

RxList:http://www.rxlist.com/pristiq-drug.htm
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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