The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	xylometazoline
Synonyms	C16H24N2 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole
ID	http://purl.obolibrary.org/obo/dinto_DB06694
activates	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
AHFScode	52:32.00
ATCCode	R01AB06 S01GA03 R01AA07
binds	http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_1581
CASRN	526-36-3
DBBrand	otrivine otrix otrivin otriven
DBSynonym	xylomethazoline
Definition	A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
InChI	InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)
InChIKey	InChIKey=HUCJFAOMUPXHDK-UHFFFAOYSA-N
label	xylometazoline
modulates	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
prefixIRI	obo2:dinto_DB06694
prefLabel	xylometazoline
SMILES	CC1=CC(=CC(C)=C1CC1=NCCN1)C(C)(C)C
Synonym	C16H24N2 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole
xref	IUPHAR:517 PharmGKB:PA165958368 Wikipedia:http://en.wikipedia.org/wiki/Xylometazoline ChemSpider:5507 PubChem Compound:5709 RxList:http://nosesprays.info/result.php?Keyword Guide To Pharmacology:517 PubChem Substance:99443248 BindingDB:50027068
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_10082	CHEBI	LOOM
http://purl.bioontology.org/ontology/ATC/S01GA03	ATC	LOOM
http://purl.jp/bio/4/id/200906065091076536	IOBC	LOOM
http://purl.bioontology.org/ontology/NDDF/004727	NDDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_10082	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10082	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10082	DDSS	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87749	NCIT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-97370	SNMI	LOOM
http://purl.bioontology.org/ontology/VANDF/4020518	VANDF	LOOM
http://purl.bioontology.org/ontology/ATC/R01AA07	ATC	LOOM
http://www.drugbank.ca/drugs/DB06694	FTC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372841007	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C009695	RH-MESH	LOOM
http://stirdf.jst.go.jp/id/200907067495371120	IOBC	LOOM
http://purl.bioontology.org/ontology/RXNORM/39841	RXNORM	LOOM
https://go.drugbank.com/drugs/DB06694	MDM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0078643	OCHV	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148237	NDFRT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15059	OCHV	LOOM
http://purl.bioontology.org/ontology/RCD/x01Cf	RCD	LOOM
http://purl.obolibrary.org/obo/DRON_00017565	SCDO	LOOM
http://purl.bioontology.org/ontology/MESH/C009695	MESH	LOOM
http://purl.bioontology.org/ontology/ATC/R01AB06	ATC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026807	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/NCIT_C87749	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10082	DRON	LOOM