The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

tocilizumab
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB06273
AHFScode

92:36
ATCCode

L04AC07
binds

http://purl.obolibrary.org/obo/dinto_1472
CASRN

375823-41-9
DBBrand

actemra
DBSynonym

atlizumab

mra

roactemra?

r-1569
Definition

Tocilizumab is a recombinant, humanized, anti-human interleukin 6 (IL-6) receptor monoclonal antibody that achieves a significant therapeutic response rate. The light chain is made up of 214 amino acids. The heavy chain is made up of 448 amino acids. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds. FDA approved on January 8, 2010.
has pharmacological target

http://purl.obolibrary.org/obo/dinto_1472
label

tocilizumab
may interact with

http://purl.obolibrary.org/obo/CHEBI_9150

http://purl.obolibrary.org/obo/dinto_DB06674

http://purl.obolibrary.org/obo/dinto_DB00514

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/CHEBI_7772
prefixIRI

obo2:dinto_DB06273
prefLabel

tocilizumab
related with

http://purl.obolibrary.org/obo/dinto_1472
xref

National Drug Code Directory:50242-137-01

Drugs.com:http://www.drugs.com/international/tocilizumab.html

RxList:http://www.rxlist.com/actemra-drug.htm

PharmGKB:PA165292659

Wikipedia:http://en.wikipedia.org/wiki/Tocilizumab
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/PDQ/CDR0000713832 PDQ LOOM
http://purl.obolibrary.org/obo/CHEBI_64360 CHEBI LOOM
http://purl.obolibrary.org/obo/DRON_00019607 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00019607 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00019607 INBANCIDO LOOM
http://purl.obolibrary.org/obo/DRON_00019607 HOIP LOOM
http://purl.obolibrary.org/obo/DRON_00019607 COVID-19 LOOM
http://purl.obolibrary.org/obo/DRON_00019607 DDSS LOOM
http://purl.obolibrary.org/obo/DRON_00019607 CIDO LOOM
http://purl.obolibrary.org/obo/DRON_00019607 ODNAE LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000180629 NDFRT LOOM
http://purl.bioontology.org/ontology/NDDF/013198 NDDF LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000713832 PDQ LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00294 OCIMIDO LOOM
http://purl.bioontology.org/ontology/RXNORM/612865 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_64360 BERO LOOM
http://purl.bioontology.org/ontology/ATC/L04AC07 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026122 PMAPP-PMO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629 ODAE LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629 CIDO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84217 NCIT LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00481 COID LOOM
http://purl.bioontology.org/ontology/MESH/C502936 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/444648007 SNOMEDCT LOOM
http://www.drugbank.ca/drugs/DB06273 FTC LOOM
https://go.drugbank.com/drugs/DB06273 MDM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU065080 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4029705 VANDF LOOM
http://bmi.utah.edu/ontologies/peontology/C1609165 RAO LOOM
http://purl.bioontology.org/ontology/LNC/LP420287-7 LOINC LOOM
http://purl.jp/bio/4/id/200906055820639940 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C502936 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C84217 BERO LOOM