The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

fosamprenavir
Synonyms

{[(2R,3S)-1-[N-(2-methylpropyl)(4-aminobenzene)sulfonamido]-3-({[(3S)-oxolan-3-yloxy]carbonyl}amino)-4-phenylbutan-2-yl]oxy}phosphonic acid

C25H36N3O9PS

ID

http://purl.obolibrary.org/obo/dinto_DB01319

AHFScode

08:18.08.08

ATCCode

J05AE07

binds

http://purl.obolibrary.org/obo/dinto_3326

http://purl.obolibrary.org/obo/dinto_0901

CASRN

226700-79-4

DBBrand

telzir

lexiva

Definition

Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.

has effect

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000613

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0001052

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000890

http://purl.obolibrary.org/obo/OAE_0000402

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3326

InChI

InChI=1S/C25H36N3O9PS/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32)/t21-,23-,24+/m0/s1

InChIKey

InChIKey=MLBVMOWEQCZNCC-OEMFJLHTSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_3326

http://purl.obolibrary.org/obo/dinto_0901

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

is substrate of

http://purl.obolibrary.org/obo/dinto_0901

label

fosamprenavir

may interact with

http://purl.obolibrary.org/obo/dinto_DB00906

http://purl.obolibrary.org/obo/dinto_DB00683

http://purl.obolibrary.org/obo/CHEBI_8212

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_119573

http://purl.obolibrary.org/obo/CHEBI_4317

http://purl.obolibrary.org/obo/CHEBI_71940

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/dinto_DB00541

http://purl.obolibrary.org/obo/dinto_DB00243

http://purl.obolibrary.org/obo/CHEBI_10127

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_9150

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_40303

http://purl.obolibrary.org/obo/dinto_DB01370

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_31794

http://purl.obolibrary.org/obo/dinto_DB01323

http://purl.obolibrary.org/obo/dinto_DB00570

http://purl.obolibrary.org/obo/CHEBI_3761

http://purl.obolibrary.org/obo/CHEBI_10125

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/dinto_DB01558

http://purl.obolibrary.org/obo/CHEBI_2611

http://purl.obolibrary.org/obo/CHEBI_75988

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/CHEBI_39548

http://purl.obolibrary.org/obo/dinto_DB01378

http://purl.obolibrary.org/obo/CHEBI_480999

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_6807

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_32315

http://purl.obolibrary.org/obo/CHEBI_63628

http://purl.obolibrary.org/obo/CHEBI_421707

http://purl.obolibrary.org/obo/dinto_DB01118

http://purl.obolibrary.org/obo/CHEBI_9139

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_49575

http://purl.obolibrary.org/obo/dinto_DB00690

http://purl.obolibrary.org/obo/dinto_DB01373

http://purl.obolibrary.org/obo/CHEBI_3061

http://purl.obolibrary.org/obo/CHEBI_2896

http://purl.obolibrary.org/obo/CHEBI_119915

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB02703

http://purl.obolibrary.org/obo/CHEBI_9674

http://purl.obolibrary.org/obo/CHEBI_64318

http://purl.obolibrary.org/obo/CHEBI_70735

http://purl.obolibrary.org/obo/CHEBI_46295

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/CHEBI_4562

prefixIRI

obo2:dinto_DB01319

prefLabel

fosamprenavir

SMILES

CC(C)CN(C[C@@H](OP(O)(O)=O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)C1=CC=C(N)C=C1

Synonym

{[(2R,3S)-1-[N-(2-methylpropyl)(4-aminobenzene)sulfonamido]-3-({[(3S)-oxolan-3-yloxy]carbonyl}amino)-4-phenylbutan-2-yl]oxy}phosphonic acid

C25H36N3O9PS

xref

PubChem Compound:131536

ChemSpider:116245

Wikipedia:http://en.wikipedia.org/wiki/Fosamprenavir

RxList:http://www.rxlist.com/cgi/generic/lexiva.htm

Drugs Product Database (DPD):2261545

National Drug Code Directory:0173-0721-00

Drugs.com:http://www.drugs.com/cdi/fosamprenavir.html

PubChem Substance:46504901

PharmGKB:PA10084

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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