Preferred Name |
retapamulin |
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Synonyms |
C30H47NO4S (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan-6-yl 2-{[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate |
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ID |
http://purl.obolibrary.org/obo/dinto_DB01256 |
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CASRN |
224452-66-8 |
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DBBrand |
altabax (glaxo) |
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DBSynonym |
sb 275833 |
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Definition |
Retapamulin is a topical antibiotic developed by GlaxoSmithKline. It was approved by the United States Food and Drug Administration in April 2007 for the treatment of bacterial skin infections such as impetigo. It is marketed as an ointment under the name brand Altabax. |
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has effect |
http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 |
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has pharmacological target | ||
InChI |
InChI=1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1 |
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InChIKey |
InChIKey=STZYTFJPGGDRJD-FJJJPKKESA-N |
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inhibits | ||
is metabolised by | ||
label |
retapamulin |
|
prefixIRI |
obo2:dinto_DB01256 |
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prefLabel |
retapamulin |
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SMILES |
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CSC1C[C@@H]2CC[C@H](C1)N2C |
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Synonym |
C30H47NO4S (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan-6-yl 2-{[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate |
|
xref |
Wikipedia:http://en.wikipedia.org/wiki/Retapamulin Drugs.com:http://www.drugs.com/cdi/retapamulin-ointment.html National Drug Code Directory:0007-5180-05 RxList:http://www.rxlist.com/cgi/generic/altabax.htm PharmGKB:PA164749341 |
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subClassOf |