The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

oxymorphone
Synonyms

C17H19NO4

(1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one

ID

http://purl.obolibrary.org/obo/dinto_DB01192

activates

http://purl.obolibrary.org/obo/dinto_2787

binds

http://purl.obolibrary.org/obo/dinto_2787

http://purl.obolibrary.org/obo/dinto_0760

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

blocks

http://purl.obolibrary.org/obo/dinto_0760

CASRN

76-41-5

DBBrand

opana

numorphan

opana er

DBSynonym

dihydrohydroxymorphinone

en3202

14-hydroxydihydromorphinone

oximorphonum

oxymorphine

dihydroxymorphinone

Definition

An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2787

InChI

InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1

InChIKey

InChIKey=UQCNKQCJZOAFTQ-ISWURRPUSA-N

is metabolised by

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

is substrate of

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

label

oxymorphone

may interact with

http://purl.obolibrary.org/obo/CHEBI_3699

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/dinto_DB06274

modulates

http://purl.obolibrary.org/obo/dinto_0760

http://purl.obolibrary.org/obo/dinto_2787

prefixIRI

obo2:dinto_DB01192

prefLabel

oxymorphone

SMILES

[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1(O)CCC2=O

Synonym

C17H19NO4

(1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one

xref

RxList:http://www.rxlist.com/cgi/generic2/oxymorphone.htm

Wikipedia:http://en.wikipedia.org/wiki/Oxymorphone

Drugs Product Database (DPD):1916505

National Drug Code Directory:63481-612-70

Drugs.com:http://www.drugs.com/cdi/oxymorphone.html

PubChem Compound:5284604

ChemSpider:4447650

PharmGKB:PA450748

BindingDB:50001707

PubChem Substance:46505296

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/LP15176-8 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/7814 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/24751001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D010111 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.497.607.675 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/N02AA11 ATC LOOM
http://stirdf.jst.go.jp/id/200907083192695441 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0030073 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4019871 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU069682 LOINC LOOM
http://purl.bioontology.org/ontology/SNMI/C-606E0 SNMI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29314 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010111 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB01192 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9161 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.723.795.576.692 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D010111 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LA28616-3 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.249.562.692 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060436 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C29314 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0011116 OMIT LOOM
http://purl.bioontology.org/ontology/NDDF/004623 NDDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147956 NDFRT LOOM
https://go.drugbank.com/drugs/DB01192 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.607.675 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7865 DRON LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018040 PMAPP-PMO LOOM
http://purl.jp/bio/4/id/200906004403074782 IOBC LOOM