The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

cefuroxime
Synonyms

(6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C16H16N4O8S
ID

http://purl.obolibrary.org/obo/dinto_DB01112
AHFScode

08:12.06.08
ATCCode

J01DC02
binds

http://purl.obolibrary.org/obo/dinto_4015

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_2004
CASRN

55268-75-2
DBBrand

elobact

cefuril

sharox

cefurax

zinnat

zinacef

kefurox

zinat

ceftin

oraxim

cepazine

biofuroksym
DBSynonym

cefuroxime [usan:ban:inn]

cefuroximo [inn-spanish]

cefuroximum [inn-latin]

cefuroxim
Definition

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus. [PubChem]
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0001333

http://purl.obolibrary.org/obo/OAE_0000975

http://purl.obolibrary.org/obo/OAE_0001707

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000476

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000851

http://purl.obolibrary.org/obo/OAE_0001105

http://purl.obolibrary.org/obo/OAE_0000327

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000811
has pharmacological target

http://purl.obolibrary.org/obo/dinto_4015
InChI

InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1
InChIKey

InChIKey=JFPVXVDWJQMJEE-IZRZKJBUSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_4015

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_2004
label

cefuroxime
may interact with

http://purl.obolibrary.org/obo/dinto_DB00798

http://purl.obolibrary.org/obo/dinto_DB00955

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/CHEBI_2637

http://purl.obolibrary.org/obo/CHEBI_8426
prefixIRI

obo2:dinto_DB01112
prefLabel

cefuroxime
SMILES

[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CC=CO1)C(O)=O
Synonym

(6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C16H16N4O8S
xref

PharmGKB:PA448868

PDB:CES

Drugs Product Database (DPD):2242657

RxList:http://www.rxlist.com/cgi/generic/cefurox.htm

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cef1076.shtml

ChEBI:3515

Drugs.com:http://www.drugs.com/cdi/cefuroxime.html

Wikipedia:http://en.wikipedia.org/wiki/Cefuroxime

National Drug Code Directory:0469-7220-01
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/ARO_0000063 ARO LOOM
https://go.drugbank.com/drugs/DB01112 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61669 NCIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147760 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4019668 VANDF LOOM
http://purl.obolibrary.org/obo/XCO_0001088 XCO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372833007 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002444 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0003774 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/S01AA27 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.190.190.165 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Cefuroxime GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.190.190.165 RH-MESH LOOM
http://purl.jp/bio/4/id/200906082611500095 IOBC LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cefuroxime SEPON LOOM
http://purl.bioontology.org/ontology/LNC/MTHU027952 LOINC LOOM
http://purl.obolibrary.org/obo/ARO_0000063 ARO LOOM
http://purl.obolibrary.org/obo/NCIT_C61669 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015887 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0007562 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D002444 BERO LOOM
http://purl.bioontology.org/ontology/ATC/J01DC02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP32648-5 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2572 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D002444 MESH LOOM
http://stirdf.jst.go.jp/id/200907032419857059 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-53360 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_3515 EFO LOOM
http://purl.bioontology.org/ontology/RXNORM/2194 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.190.190.165 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/e68.. RCD LOOM