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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | neomycin | |
| Synonyms |
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol C23H46N6O13 |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB00994 |
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| AHFScode |
84:04.04 52:04.04
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| ATCCode |
S03AA01 R02AB01 A07AA01 J01GB05 A01AB08 S01AA03 S02AA07 B05CA09 D09AA01 S01AA07 D06AX04
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| binds | ||
| CASRN |
1404-04-2
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| DBBrand |
biosol mycifradin neomix neobiotic tuttomycin endomixin myacine fraquinol mycifradin-n myacyne neolate fradiomycin bykomycin lidamycin creme nivemycin vonamycin powder v neobrettin neo-fradin neo-mantle creme myciguent neo-rx fradiomycin sulfate neofracin
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| DBSynonym |
neomycin b sulfate usaf cb-19 caswell no. 595 neomycin sulphate neomycin sulfate
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| Definition |
A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed). Neomycin is a bactericidal aminoglycoside antibiotic that binds to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and acceptor tRNA sites and results in the production of non-functional or toxic peptides.
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| has effect | ||
| has pharmacological target | ||
| InChI |
InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
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| InChIKey |
InChIKey=PGBHMTALBVVCIT-VCIWKGPPSA-N
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| inhibits | ||
| label |
neomycin
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| may interact with |
http://purl.obolibrary.org/obo/CHEBI_3499 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/CHEBI_204928 http://purl.obolibrary.org/obo/CHEBI_3508 http://purl.obolibrary.org/obo/CHEBI_29007 http://purl.obolibrary.org/obo/CHEBI_209807 |
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| prefixIRI |
obo2:dinto_DB00994
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|
| prefLabel |
neomycin
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| SMILES |
NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
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| Synonym |
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol C23H46N6O13
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| xref |
RxList:http://www.rxlist.com/cgi/generic3/neomy.htm National Drug Code Directory:39822-0310-5 PDB:CNY ChEBI:7507 ChemSpider:8075 PubChem Substance:46505525 Drugs.com:http://www.drugs.com/cdi/neomycin.html PubChem Compound:8378 PharmGKB:PA450608 Wikipedia:http://en.wikipedia.org/wiki/Neomycin Drugs Product Database (DPD):527750
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| subClassOf |
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