The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

pemirolast

Synonyms

C10H8N6O

9-methyl-3-(2H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

ID

http://purl.obolibrary.org/obo/dinto_DB00885

CASRN

100299-08-9

DBBrand

alamast

DBSynonym

pemirolast potassium

pemirolastum [inn-latin]

pemiroplast potassium

Definition

Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.

InChI

InChI=1S/C10H8N6O/c1-6-3-2-4-16-9(6)11-5-7(10(16)17)8-12-14-15-13-8/h2-5H,1H3,(H,12,13,14,15)

InChIKey

InChIKey=HIANJWSAHKJQTH-UHFFFAOYSA-N

label

pemirolast

prefixIRI

obo2:dinto_DB00885

prefLabel

pemirolast

SMILES

CC1=CC=CN2C(=O)C(=CN=C12)C1=NNN=N1

Synonym

C10H8N6O

9-methyl-3-(2H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

xref

PubChem Substance:46509034

PharmGKB:PA164781018

National Drug Code Directory:68669-711-10

Drugs.com:http://www.drugs.com/cdi/pemirolast.html

ChemSpider:51990

RxList:http://www.rxlist.com/cgi/generic/alamast.htm

PubChem Compound:57697

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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