The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	daunorubicin
Synonyms	C27H29NO10 (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
ID	http://purl.obolibrary.org/obo/dinto_DB00694
AHFScode	10:00.00
ATCCode	L01DB02
binds	http://purl.obolibrary.org/obo/dinto_2868 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_2828 http://purl.obolibrary.org/obo/dinto_2751 http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_2998 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1973 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1993 http://purl.obolibrary.org/obo/dinto_3489
CASRN	20830-81-3
DBBrand	dm1 daunarubicinum rubidomycin hydrochloride daunomycin, hydrochloride daunamycin daunoxome daunomycin daunorubicinum [inn-latin] daunorubicin hydrochloride daunomycin hydrochloride cerubidin daunorubicin, hydrochloride daunoblastin rubomycin c antibiotics from streptomyces coeruleorubidus leukaemomycin c rp 13057 hydrochloride daunorubicin hcl cerubidine daunorubicine rcra waste no. u059 acetyladriamycin anthracyline daunorrubicina rubidomycin ondena
Definition	A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0001297 http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001397 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001281 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0001205 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000466 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_2868 http://purl.obolibrary.org/obo/dinto_2751
InChI	InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1
InChIKey	InChIKey=STQGQHZAVUOBTE-VGBVRHCVSA-N
induces	http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_1440
inhibits	http://purl.obolibrary.org/obo/dinto_2868 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_2828 http://purl.obolibrary.org/obo/dinto_2751
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_2998 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_2998 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1973 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1993 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3489 http://purl.obolibrary.org/obo/dinto_2828
is transported by	http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1973 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1993 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3489 http://purl.obolibrary.org/obo/dinto_2828
label	daunorubicin
may interact with	http://purl.obolibrary.org/obo/dinto_DB00072
prefixIRI	obo2:dinto_DB00694
prefLabel	daunorubicin
related with	http://purl.obolibrary.org/obo/dinto_2873
SMILES	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
Synonym	C27H29NO10 (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
xref	RxList:http://www.rxlist.com/cgi/generic2/daunorubicin.htm PubChem Compound:30323 National Drug Code Directory:0703-5233-13 PDB:BNR Drugs.com:http://www.drugs.com/cdi/daunorubicin.html ChEBI:4330 PharmGKB:PA449212 Wikipedia:http://en.wikipedia.org/wiki/Daunorubicin PubChem Substance:46508433 ChemSpider:28163 Drugs Product Database (DPD):2231420
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.562.050.200	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D09.408.051.059.200	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D003630	BERO	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0011015	HFO	LOOM
http://purl.bioontology.org/ontology/NDDF/004821	NDDF	LOOM
http://purl.bioontology.org/ontology/RCD/h29..	RCD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003630	RH-MESH	LOOM
http://purl.bioontology.org/ontology/VANDF/4019704	VANDF	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372715008	SNOMEDCT	LOOM
http://www.drugbank.ca/drugs/DB00694	FTC	LOOM
http://purl.bioontology.org/ontology/RXNORM/3109	RXNORM	LOOM
http://www.ifomis.org/acgt/1.0#Daunorubicin	ACGT-MO	LOOM
http://purl.bioontology.org/ontology/ATC/L01DB02	ATC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011015	OCHV	LOOM
http://purl.bioontology.org/ontology/CSP/0192-2446	CRISP	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62091	NCIT	LOOM
http://purl.jp/bio/4/id/200906017660174563	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0004913	OMIT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016927	PMAPP-PMO	LOOM
http://stirdf.jst.go.jp/id/200907015875490009	IOBC	LOOM
http://purl.obolibrary.org/obo/NCIT_C62091	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	CIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_41977	NIFSTD	LOOM
http://purl.bioontology.org/ontology/MESH/D003630	MESH	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147796	NDFRT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3620	OCHV	LOOM
http://purl.bioontology.org/ontology/SNMI/C-780B0	SNMI	LOOM
http://www.co-ode.org/ontologies/galen#Daunorubicin	GALEN	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.562.050.200	RH-MESH	LOOM
https://go.drugbank.com/drugs/DB00694	MDM	LOOM